Abstract
Exo-terrestrial biology hits the core questions of modern science, where we are from and how we will be. Once we understand the function and mechanism of living systems in detail, we recognize a missing link between pre-biotic chemical evolution and the original ancestor of life. Space exploration searching extraterrestrial life on other planetary bodies might contribute to answer whether the principle that governs terrestrial life is limited specifically to earth or could be generalized to the universal law. Mass spectrometry has been an effective tool in this research field. In order to survey extant lives and fossil record, highly bio-specific and sensitive method should be selected. We can expect spin off from space driven technology development for which many severe requirements are imposed, such as physical size, mass, power consumption, and maintenance. Electrospray might be one of candidate technologies for space exploration at its capability to analyze bioassociated chemical species at high sensitivity and its wide range of applicability.