Abstract
A number of studies have appeared recently on the underlying mechanism of liposome-cell interactions under in vitro conditions, in which isolated cell populations or cell lines were used. However, our knowledge of how liposomes interact with cells, how liposomal physicochemical properties such as size, charge or fluidity, influence the interactions and the parameters that influence this in vivo is limited. We will summarize and discuss the relevant studies on this matter in this review.