Abstract
Biophysical chemistry of biointerfaces is discussed along the line of a theoretical model suitable for biointerfaces, that is, a soft particle theory. In this theory, biointerfaces such as cell surfaces and their model surfaces are regarded as a solid surface covered with an ion-penetrable polyelectrolyte layer. Electrokinetic phenomena of soft particles and electrostatic interactions between soft surfaces are quite different from those for hard particles without surface structures. Recent progress in theories for interfacial electric phenomena of soft particles are reviewed.