Abstract
A new cosmetic ASPION CE was commercialized by utilizing a novel surfactant coating technique for L–ascorbicacid phosphate magnesium salt (Vitamin C).The coating technique can change the surface properties of cosmeticingredients. In developing the ASPION CE, the hydrophilic property of ascorbic acid derivative was converted to thehydrophobic one, which enables to dissolve it in natural oils. As the result, we can completely dissolve the coatedVitamin C and the hydrophobic Vitamin E in an oil phase, and can get a homogeneous cosmetic oil. The particlesizes can be controlled around several hundreds nanometer by changing preparation conditions. The oil–based cos-metic was available for carrying the Vitamin C to the melanosite through the cutaneous tissue, because the outer skinis hydrophobic. Furthermore, immobilized Vitamin C was stabilized by coating with the surfactant layer.
