Abstract
Postoperative peritoneal adhesions cause pelvic pain, bowel obstruction, and infertility. Repeated hepatic resections with presence of adhesions induced by previous hepatectomies are time–consuming and hazardous. We recently developed a new hepatectomy–induced postoperative adhesion rat model to evaluate the anti-adhesion efficacy of commercially available sheet materials (Seprafilm® and Interceed®) and the recently reported hyaluronan–based in situ cross–linkable hydrogels. Adhesions between the liver surface and the diaphragm and adhesions around the hepatic hilum were less severe, but were not remarkably reduced by the anti-adhesion materials.
