2019 年 44 巻 5 号 p. 239-246
This review describes the construction of artificial cell membrane and its applications. Planar lipid bilayers are used for functional studies of ion channels and nanopore sensing. We have used microfabrication and microfluidic technologies that have a significant advantage: easy to handle lipid molecules or solution at the micron scale. Applying these advantages, we propose a stable and reproducible preparation procedure for the planar lipid bilayers using “droplet contact method”, and they are applying to extensive applications, such as assay for transmembrane peptides, microRNA detection with DNA computing, and ion conductance probe.