Abstract
Biomaterials have been widely investigated as a tool to be applied for regenerative medicine. In the past three decades, it has been demonstrated that three–dimensional porous scaffolds with cells as well as biodegradable drug delivery vehicles with a growth factor could enhance regeneration of tissues, such as skin, bone, cartilage, blood vessel, nerve, in clinical treatments. On the contrary, recent advancement in stem cell biology enables us to utilize stem cells for developing regenerative medicine and drug researches, and these developments need new biomaterials to control cell proliferation, differentiation, and tissue construction. In this article, recent challenges in biomaterials– based regenerative medicine will be discussed.