抄録
Biological membranes comprise phospholipids that are acylated with various fatty acids. The fatty acid compositions of bacterial biomembranes are properly regulated to maintain membrane homeostasis and alleviate external stresses. Although the substrate selectivity of acyltransferases that introduce fatty acyl groups during de novo phospholipid biosynthesis is supposed to be one factor regulating the fatty acid compositions, their enzymatic and physiological functions are poorly studied. In this minireview, how bacteria regulate the membrane fatty acid compositions via the acyltransferase system and how it is relevant to cell physiology are presented.