Abstract
Cells are the smallest units of life. Biomembranes play an important role in separating the cell interior from the external environment and creating fields of chemical reactions and biosynthesis necessary for maintenance of life phenomena. Membrane curvature formation is observed in various biological phenomena, such as the cellular uptake of nutrients and secretion of extracellular vesicles carrying informative molecules. Curvature–sensing peptides are promising tools that allow us to visualize curved membranes or manipulate biological phenomena. In this review, I would like to introduce the technology and applications of curvature–sensing peptides for detection, isolation, modification, and drug delivery system of extracellular vesicles.
