MEMBRANE
Online ISSN : 1884-6440
Print ISSN : 0385-1036
ISSN-L : 0385-1036
Special Topic : Boron Neutron Capture Therapy (BNCT) : Recent Advances from Basic Research to Clinical Studies
Role of PET in BNCT
Yasukazu Kanai
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2026 Volume 51 Issue 2 Pages 72-75

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Abstract
PET imaging visualizes biological functions using radiolabeled compounds, with [18F]FDG widely used for cancer diagnosis. In BNCT, [18F]FBPA is valuable because it reflects the biodistribution of the boron drug BPA, allowing prediction of treatment effectiveness through tumor uptake. This has been essential for the clinical adoption of BPA–BNCT. PET also supports drug–development studies by enabling noninvasive tracking of pharmacokinetics.
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