There has been a demand for such hemodialysis membranes of better biocompatibility the use of which would reduce the incidence of complications in patients who have been under long hemodialysis treatment.
We have developed a surface modification technique, consisting of forming efficiently a synthetic polymer layer on the inside of the regenerated cellulose hollow fiber without impairing fiber performance. Our newly-developed membrane has an excellent biocompatibility by modifying the inner surface and by immobilizing Vitamin E (α-tocopherol), which serves as an antioxidant, to the modified surface.
