Control Membrane in Transdermal Therapeutic Systems (TTS)

Abstract

Transdermal Therapeutic System (TTS) which controls drug release by a membrane has been introduced. The system consists of five parts, that is, a backing film, a drug reservoir, a control membrane, an adhesive layer and a release liner. The release of nitroglycerin from the system is almost nearly zero order, enabling a constant drug administration to the body for over 24 hours. The control membrane material (ethylene-vinyl acetate copolymer) was also briefly described.