生体膜における両親媒性ペプチドの機能

抄録

Integral membrane proteins contain the hydrophobic peptide segments spanning lipid hydrocarbon layer and, for functional proteins within the membrane, also contain the amphiphilic peptide segments. The former may be called the “stabilization” peptide and the latter for the “functional” peptide. Membrane proteins in enveloped viruses have the fusion and hemolytic activities. They contain the hydrophobic or amphiphilic peptide segments. We calculate the mean hydrophobicity and the mean hydrophobic moment for these petides and discuss their functions based on these data.