A membrane Oxygenator is widely used for open heart surgery. The function of the Oxygenator is to remove carbon dioxide from the venous blood and replace it with oxygen to maintain the metabolism of the patient.
This review focuses on the mechanism of gas exchange and surface modifications of material for the membrane Oxygenator. Regarding the surface modifications, the biocompatibility of hepar in coated membrane and newly developed polymer coated membrane is introduced.