Comparative Evaluation of micro-particles of different materials by M-DIN ICP-MS

Shunsuke Hosoda; Takashi Ohta; Satoshi Kohno; Tomoko Miyake; Takahiro Iwai; Koichi Chiba; Akitoshi Okino

doi:10.11299/metallomicsresearch.MR202301

Regular article

Comparative Evaluation of micro-particles of different materials by M-DIN ICP-MS

Shunsuke Hosoda, Takashi Ohta, Satoshi Kohno, Tomoko Miyake, Takahiro Iwai, Koichi Chiba, Akitoshi Okino

著者情報

Shunsuke Hosoda
Laboratory for Future Interdisciplinary Research of Science and Technology, Tokyo Institute of Technology, J2-32, 4259 Nagatsuta, Midori-ku, Yokohama 226-8502 [日本]
Takashi Ohta [日本]
https://orcid.org/0000-0003-3834-5605
Laboratory for Future Interdisciplinary Research of Science and Technology, Tokyo Institute of Technology, J2-32, 4259 Nagatsuta, Midori-ku, Yokohama 226-8502 [日本]
Satoshi Kohno
Laboratory for Future Interdisciplinary Research of Science and Technology, Tokyo Institute of Technology, J2-32, 4259 Nagatsuta, Midori-ku, Yokohama 226-8502 [日本]
Tomoko Miyake
Laboratory for Future Interdisciplinary Research of Science and Technology, Tokyo Institute of Technology, J2-32, 4259 Nagatsuta, Midori-ku, Yokohama 226-8502 [日本]
Takahiro Iwai
Forensic Science Group, RIKEN SPring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5198 [日本]
Koichi Chiba
Department of Applied Chemistry for Environment, Kwansei Gakuin University, 2-1 Gakuen, Sanda, Hyogo 669-1337 [日本]
Akitoshi Okino [日本]
https://orcid.org/0000-0002-8949-294X
Laboratory for Future Interdisciplinary Research of Science and Technology, Tokyo Institute of Technology, J2-32, 4259 Nagatsuta, Midori-ku, Yokohama 226-8502 [日本]

キーワード: ICP-MS, Single-cell analysis, Micro-droplet injection system, Desolvation system, Micro particles, Elemental analysis

ジャーナルオープンアクセス HTML

2023 年 3 巻 1 号 p. reg01-reg06

DOI https://doi.org/10.11299/metallomicsresearch.MR202301

詳細

抄録

In this study, artificial microparticles were used as pseudo-cells to select samples that can be used as substitutes for micro-droplet injection nebulizer (M-DIN) ICP-MS standards. The microparticles were selected on the basis that they should be comparable in size to human cells, have a small deviation in volume, and have different elemental contents and pyrolysis properties. Polymer latex particles, magnetic latex particles, borosilicate glass particles, and straight polymethyl methacrylate particles were used. As a result, we succeeded in detecting the contained elements in polymer latex, magnetic latex and polymethyl methacrylate particles. In addition, focusing on Mg contained in all particles, we compared the correlation between the mass signal intensity by droplet ICP-MS and the average elemental content in a particle.

責任著者(Corresponding author)

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