Development of a new HLA allele assignment program, Sequence Alignment Based Assigning Software (SeaBass)

Abstract

Development of HLA allele assignment methods using numerous numbers of NGS data is necessary for simplification and acceleration of the NGS-based HLA genotyping. We developed a new HLA allele assignment program, Sequence Alignment Based Assigning Software (SeaBass) that has an extremely high accuracy. Therefore, the program is thought to be one of excellent allele assignment tools to detect new and null HLA alleles.