This paper proposes some advanced data acquisition methods for the quantitative single photon emission CT. One example of such methods is the odd number angular sampling method over 360 degrees for a widely distributed object, and the other is fine angular sampling of 180 degrees For a localized small object. The image quality thus obtain such as the spatial resolution and the signal to noise ratio becomes better than that reconstructed from the conventional conjugate projection data. The reconstruction technique used in computer simulation is the iterated correction matrix method, but other techniques are also applicable. Comparison between the weighted back projection method and the correction matrix method is also presented