Abstract
This manuscript overviews methods that register microscopic pathology images. A microscopic pathology image is two-dimensional and is captured from a thin section of a specimen extracted from a patient. The methods overviewed by this manuscript play a core role in reconstruction of 3-dimensional microscopic pathology images. A 3D pathology image is reconstructed from a set of many 2D pathology images, which capture thin sections sequentially sliced from one specimen. Piling these images up, one can reconstruct a 3D pathology image. One problem to be solved for the 3D reconstruction is the compensation of independent non-rigid deformation of the thin-sections. Non-rigid registration of given 2D pathology images is required for the reconstruction of appropriate 3D microscope images. The author of this manuscript first points out problems specific to the registration for the 3D reconstruction and then describes several methods for the registration.
