Brain Network Analysis

Abstract

MRI is essential for the early and differential diagnosis of Alzheimerʼs disease and for the evaluation of its progression. Three-dimensional T1-weighted images can be acquired easily in routine clinical practice, and have recently been applied to network analysis. In recent years, T1-weighted images have also been applied to network analysis. In addition, a method that focuses on the similarity of gray matter has made it possible to detect network abnormalities at the individual level. These new methods contribute to the understanding of the pathogenesis of Alzheimerʼs disease by allowing us to examine the effects of amyloid-𝛽 and tau protein accumulation on white matter connectivity and brain networks.