Radiogenomics for Lung Cancer

Abstract

Radiogenomics for lung cancer can be considered a “dry biopsy” and may support conventional wet biopsy. It may provide gene-related information of patients with lung cancer, who cannot undergo conventional biopsy or have spatially heterogeneous tumors. In this review paper, we share the basic flows and results of our research on radiogenomics, which focused on discovery of associations between image features and genes in lung cancer, developments of prediction models for HOPX, EGFR mutation, and its subtypes.