Main Topic / MR Linac and Radiogenomics for Cancer Therapy
Radiogenomics for Breast Cancer
2023 Volume 41 Issue 2 Pages 67-72
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2023 Volume 41 Issue 2 Pages 67-72
Advances in post-genome research have revealed the molecular and genetic characteristics of cancer. By using these knowledge, molecular targeted drugs have also been developed. Precision medicine, in which treatment is com bined with molecular classification based on the cancer genotype, is being performed in clinical practice. Radiogenomics is research to estimate genotype from cancer phenotype, and its purpose is to create innovations to maintain the competitive advantage of diagnostic imaging in cancer genomic medicine and to expand the role of imag ing test. This article describes the current state of radiogenomics for breast cancer. They are (1) subtype classification of breast cancer, (2) difference from CAD for differential diagnosis, (3) relationship with blood test, (4) prediction of the efficacy of preoperative drug therapy, and (5) application to preventive imaging medicine.
