Hypertrophic Olivary Degeneration after Gamma-knife Radiosurgery for Pontine Metastasis

Yuki SHINOHARA; Toshibumi KINOSHITA; Fumiko KINOSHITA; Toshihide OGAWA

doi:10.2463/mrms.11.299

Case Report

Hypertrophic Olivary Degeneration after Gamma-knife Radiosurgery for Pontine Metastasis

Yuki SHINOHARA, Toshibumi KINOSHITA, Fumiko KINOSHITA, Toshihide OGAWA

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Keywords: gamma-knife radiosurgery, Guillain-Mollaret triangle, hypertrophic olivary degeneration, inferior olivary nucleus, magnetic resonance image

JOURNAL OPEN ACCESS

2012 Volume 11 Issue 4 Pages 299-302

DOI https://doi.org/10.2463/mrms.11.299

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Abstract

We present a case of a 57-year-old woman who underwent gamma-knife radiosurgery (GKRS) for pontine metastasis. Magnetic resonance (MR) imaging 2.8 months after GKRS showed T₂ hyperintensity and hypertrophy of the left inferior olivary nucleus (ION) without gadolinium enhancement and smaller pontine metastasis. We diagnosed the signal change in the left ION as hypertrophic olivary degeneration (HOD) resulting from damage to the left central tegmental tract. We believe this is the first report to describe HOD after GKRS for pontine metastasis.

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