2019 Volume 18 Issue 4 Pages 276-285
To mitigate the susceptibility inhomogeneity induced by radio-frequency transmit phase error through the whole brain in quantitative susceptibility mapping (QSM) using single-echo gradient echo sequence, we developed a novel single-step QSM reconstruction algorithm and compared it with a previous algorithm in five healthy volunteers. The proposed algorithm had effectively suppressed the susceptibility inhomogeneity through the whole brain and achieved acceptable quality, similar to that of the susceptibility map calculated from a multi-echo gradient echo sequence.