Magnetic Resonance in Medical Sciences
Online ISSN : 1880-2206
Print ISSN : 1347-3182
ISSN-L : 1347-3182
Technical Notes
Increased and More Heterogeneous Gadoxetic Acid Uptake of the Liver Parenchyma after Hepatitis C Virus Eradication by Direct Antiviral Agent
Nobuhiro FujitaAkihiro NishieYoshiki AsayamaKousei IshigamiTomohiro NakayamaYasuhiro UshijimaDaisuke KakiharaYukihisa TakayamaKoichiro MoritaKeisuke IshimatsuSeiichiro TakaoTomoharu YoshizumiNorihiro FurusyoHiroshi Honda
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JOURNAL OPEN ACCESS

2020 Volume 19 Issue 4 Pages 389-393

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Abstract

We evaluated the changes of gadoxetic acid uptake of the liver parenchyma after hepatitis C virus (HCV) eradication by direct-antiviral agent (DAA) therapy. The increase rate of the liver-to-muscle signal intensity ratio, the skewness and the kurtosis were calculated in the hepatobiliary phase. After sustained virological response, gadoxetic acid uptake of the liver parenchyma increased, but became heterogeneous. Our study proved that HCV eradication by DAA therapy could significantly affect gadoxetic acid uptake.

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© 2020 by Japanese Society for Magnetic Resonance in Medicine

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