Myocardial T1-mapping and Extracellular Volume Quantification in Patients and Putative Carriers of Muscular Dystrophy: Early Experience

Kazuhiro Koyanagawa; Yuta Kobayashi; Tadao Aikawa; Atsuhito Takeda; Hideaki Shiraishi; Satonori Tsuneta; Noriko Oyama-Manabe; Hiroyuki Iwano; Toshiyuki Nagai; Toshihisa Anzai

doi:10.2463/mrms.bc.2020-0069

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引用する場合も本公開記事を引用してください。

Myocardial T₁-mapping and Extracellular Volume Quantification in Patients and Putative Carriers of Muscular Dystrophy: Early Experience

Kazuhiro Koyanagawa, Yuta Kobayashi, Tadao Aikawa, Atsuhito Takeda, Hideaki Shiraishi, Satonori Tsuneta, Noriko Oyama-Manabe, Hiroyuki Iwano, Toshiyuki Nagai, Toshihisa Anzai

著者情報

Kazuhiro Koyanagawa
Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
Yuta Kobayashi
Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
Tadao Aikawa
Department of Radiology, Jichi Medical University Saitama Medical Center
Atsuhito Takeda
Department of Pediatrics, Hokkaido University Hospital
Hideaki Shiraishi
Department of Pediatrics, Hokkaido University Hospital
Satonori Tsuneta
Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital
Noriko Oyama-Manabe
Department of Radiology, Jichi Medical University Saitama Medical Center
Hiroyuki Iwano
Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
Toshiyuki Nagai
Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University
Toshihisa Anzai
Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University

キーワード: cardiovascular magnetic resonance imaging, T₁-mapping, extracellular volume fraction, muscular dystrophy, putative carrier

ジャーナルオープンアクセス早期公開

論文ID: bc.2020-0069

DOI https://doi.org/10.2463/mrms.bc.2020-0069

この記事には本公開記事があります。

The final version of this article is now available: Vol. 20 (2021), No. 3 pp. 320-324

詳細

抄録

To assess myocardial fibrosis associated with muscular dystrophy, T₁-mapping and extracellular volume fraction (ECV) quantification was prospectively performed using cardiovascular MR (CMR) imaging in 6 male patients with muscular dystrophy and 5 female putative carriers of Duchenne or Becker muscular dystrophy. Five patients and all putative carriers had an elevated ECV (>29.5% for men and >35.2% for women), suggesting that ECV has a potential to detect diffuse fibrotic changes in patients and putative carriers of muscular dystrophy.

責任著者(Corresponding author)

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