Abstract
As mycotoxins can never be completely removed from commodities, many countries have regulated their levels in food according to their known adverse health effect. For defining the regulation level, an assessment of the health risk is required. To understand the toxic properties of mycotoxins, it is necessary to perform short-term, sub-chronic, and chronic studies at various doses using experimental animals. Also needed are carcinogenic studies in vivo and in vitro using bacteria. From each adequately performed animal study, a threshold dose, such as the NOAEL or NOEL, is defined. The value is essential for the estimation of a provisional tolerable daily intake (PMTDI). I present toxicological data and information of mycooxins that have been evaluated by JECFA.
