Abstract
It has been suggested that somatic homologous recombination is one of the important mechanisms of genetic variations in asexual life cycle of filamentous fungi. Recently, a simple detection/selection system of somatic homologous recombination was constructed by using nonfunctional fluorescence antibiotic markers in the rice blast fungus Pyricularia oryzae. Here we have summarized the detection systems of somatic homologous recombination and the current advancements of genome responses for unsuitable conditions in eukaryotes. We focused on somatic homologous recombination events induced by chemical stress treatment, and discussed the application of this mechanism to a biological marker of several mycotoxins.