JSM Mycotoxins
Online ISSN : 1881-0128
Print ISSN : 0285-1466
ISSN-L : 0285-1466
“Mold and infectious diseases”
Contribution of gliotoxin to aspergillosis
Takahito Toyotome
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JOURNAL FREE ACCESS

2015 Volume 65 Issue 2 Pages 109-113

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Abstract
  Aspergillus species (spp.) are medically important pathogens that cause aspergillosis, and A. fumigatus is the most prevalent causative agent of the disease. Aspergillus spp. produce various secondary metabolites; however, the role of these metabolites in aspergillosis remains unclear. Gliotoxin is a major secondary metabolite produced by A. fumigatus. Several recent studies have reported that gliotoxin contributes to the virulence of A. fumigatus. Here I review studies related to gliotoxin and its contribution to the infection caused by A. fumigatus.
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© 2015 Japanese Society of Mycotoxicology
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