JSM Mycotoxins
Online ISSN : 1881-0128
Print ISSN : 0285-1466
ISSN-L : 0285-1466
Regulation of kojic acid production in Aspergillus oryzae
Motoaki Sano
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2022 Volume 72 Issue 1 Pages 39-42


  Kojic acid is a secondary metabolite of Aspergillus oryzae, which was discovered after the koji mold used in the process of brewing sake was thought to contain ingredients that are beneficial to the skin. In this study, we analyzed the effect of LaeA and five velvet genes (veA, velB, velC, velD, and vosA), which are presumed to be involved in the control of kojic acid production, on the production of kojic acid by creating a gene-disruption strain. As a result, it was found that each gene has a different role in the control of kojic acid production.

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© 2022 Japanese Society of Mycotoxicology
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