抄録
The lack of reliable immunohistochemical markers available for specific and sensitive recognition of human oligodendrocytes and their neoplasms was a big issue for neuropathology for a long time. Nowadays, anti-Olig2 antibody has partially settled the problem. It faithfully immunolabels nuclei of oligodendrocytes on formalinfixed, paraffin-embedded tissue section. This is a personal history on establishment of anti-human Olig2 antibody covering from the initial concept through commercialization.