Neuro-Oncologyの進歩
Online ISSN : 2187-0551
Print ISSN : 1880-0742
ISSN-L : 1880-0742
特集 -第100回記念大会-
抗ヒトOlig2抗体の開発 - 着想から市販化までを振り返る -
横尾 英明
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ジャーナル フリー

2010 年 19 巻 1 号 p. 71-75

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抄録
The lack of reliable immunohistochemical markers available for specific and sensitive recognition of human oligodendrocytes and their neoplasms was a big issue for neuropathology for a long time. Nowadays, anti-Olig2 antibody has partially settled the problem. It faithfully immunolabels nuclei of oligodendrocytes on formalinfixed, paraffin-embedded tissue section. This is a personal history on establishment of anti-human Olig2 antibody covering from the initial concept through commercialization.
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© 2010 近畿脳腫瘍病理検討会
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