Abstract
Immunohistochemical cell kinetic analysis of brain tumors is performed with double labeling with BUdR in situ and IUdR in vitro. Double labeling study revealed mostly regular period of S-phase time among the various types of brain tumors as nine to 10 hours, and potential doubling time is varied in tumors, and well correlated with BUdR labeling index. The method will facilitate strategies of post-operative therapy and clinical follow-up.