Antiphospholipid antibody syndrome (APS), which produces various clinical manifestations including arteriovenous thrombosis, recurrent spontaneous abortion, and thrombocytopenia is recognized as one of the causes of cerebral infarction in young people. It has recently been reported that microembolic signals (MES) detected by transcranial Doppler sonography might be related to cerebral ischemia in APS patients. High intensity transient signals (HITS) were studied in a 38-year-old female with APS associated with a lupus-like condition for 15 months after cerebral infarction. Interestingly, both the number of HITS and the acoustic power of HITS increased remarkably during the acute phase. This is the first prospective case report of HITS in an APS patient who developed cerebral infarction.
