Neurotraumatology
Online ISSN : 2434-3900
Review Article
Mechanism and Prevention of Neurotrauma
Minoru FujikiHidenori Kobayashi
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JOURNAL FREE ACCESS

2009 Volume 32 Issue 2 Pages 57-60

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Abstract

The evening seminar entitled “Basic science of Neurotrauma” in the 32nd annual meeting of the Japan Society of Neurotraumatology was reviewed and discussed future strategy of treatment and prevention of the neurotrauma in this article. Fourteen original papers were presented in the sym­po­sium regarding basic mechanisms and treatment in traumatic brain injury, cerebral ischemia and spinal cord injury. The studies for treatment of the neural injury have been suc­cessfully developing because of the development of several kinds of drug therapy, and the way to manipulate genes that expresses following neuronal injury by means of inhibition of apoptosis cascades with preconditioning paradigm. Furthermore, neural regeneration strategies have been expects to facilitate functional recovery after injury. Preconditioning approach against neural injury also exhibit similar effect to expansion of the secondary injury. Accumulating evidences these neuroprotective and helpful for regenerating injured brain is a new platform to study the neuro-regeneration, potentially protect against expansion of secondary injury from injury, and design strategies for prevent and recover from neurotrauma.

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© 2009 The Japan Society of Neurotraumatology
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