神経外傷
Online ISSN : 2434-3900
原著
慢性硬膜下血腫に対するアートセレブ®脳脊髄手術用洗浄環流液による洗浄術の臨床的検討
中村 達也大橋 智生冨田 丈博岡田 博史三木 保
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ジャーナル フリー

2011 年 34 巻 2 号 p. 167-171

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Chronic subdural hematoma is thought to be an easily treatable disease. However, its recurrence rate is approximately 10%, and such cases require re-operation. We compared the recurrance rate of chronic subdural hematoma with irrigation using either saline or the artificial cerebrospinal fluid Artcereb®.

Cases: We divided the patients into 2 groups. A total of 60 patients in the normal saline group (hematoma, n=58; bilateral hematoma, n=2) underwent irrigation with saline between March 2007 and July 2009. A total of 61 patients in the Artcereb group (hematoma, n=54; bilateral hematoma, n=7) underwent irrigation using Artcereb® between August 2009 and May 2011.

Methods: We performed irrigation via 1 burr hole with 500 – 1000 ml of either normal saline or Artcereb® under local anesthesia and observed until recurrence or disappearance of the hematomas on CT scan. We researched the recurrence rate of the hematomas.

Results: Recurrence of the hematomas were observed in 8 cases (13%) in the normal saline group and 5 cases (8.2%) in the Artcereb group. No statistically significant differences were observed. Among those patients who did not receive anti­coagulants, the recurrence rate was 6/54 (11%) in the normal saline group and 1/49 (2.0%) in the Artcereb group (p<0.10).

Conclusion: Our study showed the posibility that the post­operative recurrence rate of chronic subdural hematoma was lower using Artcereb® than saline for irrigation.

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© 2011 日本脳神経外傷学会
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