3-ヒドロキシ-3-メチルブチる=アセタートからイソプレンおよびその中間体の合成

抄録

Syntheses of isoprene and its intermediates from 3-hydroxy-3-methylbutyl acetate [1], obtained by the radical addition of isopropyl alcohol to vinyl acetate, were studied. Pyrolysis of CI - gives 2-methyl-3-butene-2-ol [4] at a good yield. Acid-catalysed reaction of C over alumina affords principally isoprene, 3-methyl-3-butene-1-acetate [2] and 3-methyl-2- butene-1-acetate [3], suggesting one step synthesis' of isoprene (Fig.2). Isoprene has also been obtained by the dehydration of [4 ]and by the pyrolyses of [2] and [3].