4-アルキル,4-アルコキシシクロヘキサンカルボン酸異性体の¹³C-NMRスペクトルによる立体配座解析

抄録

Conformations of 4-alkyl- and 4-alkoxycyclohexanecarboxylic acid isomers with relatively long and linear carbon chains have been examined by ¹³C-NMR. The alkyl (butyl) derivative obtained from the corresponding benzoic acid by PtO₂, hydrogenation consists of a mixture of two configurations, trans-form and cis-form (Fig.1). Both had alkyl-equatorial conformations. Th e alkoxy (butoxy, pentyloxy, hexyloxy) products obtained by catalytic reduction over PdC contain a mixture of two forms (Fig.2). However, the cis-alkoxy compound has a different conformation from the cis-alkyl compound; the alkoxyl group is exclusively in the axial orientation.