不斉炭素上にフッ素原子を有するアミド誘導体の合成
1985 年 1985 巻 11 号 p. 2195-2198
詳細
1985 年 1985 巻 11 号 p. 2195-2198
Chiral amides, Nvhich are potentially biologically active, were prepared from both enantiousers of ethyl hydrogen 2 -alkyl-2-fluoro-malonatc. From the point of view of the moleculare design of fluorine-containing compounds having the biological activity, chiral N-(2-fluoro-3mercapto-2-methylpropionyl)proline was also prepared.
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