Abstract
Objective: The aim of this study was to determine if there was an association between metabolic syndrome (MS) and heart rate (HR).
Methods: Medical check-up data from 2,079 men and 1,215 women were examined to determine if there were associations between HR and MS-related risk factors, MS, Japanese MS (JMS), and diabetes.
Results: HR was significantly higher in MS subjects than in non-MS subjects for both men and women (p<0.0001 in men and<0.001 in women). The prevalence of MS and JMS was significantly higher in the highest quartile of HR (Q4) than in the lowest quartile (Q1) both in men and in women (p<0.0001 for both male MS and male JMS,<0.001 for female MS, and<0.01 for female JMS). The prevalence of diabetes was significantly higher in Q4 than in Q1 for men (p<0.001). HR was significantly correlated with body fat%, blood pressure, fasting glucose, triglycerides, high-sensitivity CRP, white blood cell count, gamma glutamyltransferase, alanine aminotransferase, and estimated glomerular filtration rate both in men and women. HR was also significantly correlated with body mass index, waist circumference, high-density lipoprotein cholesterol, hemoglobin A1c, and %vital capacity in men and with uric acid in women.
Conclusions: HR was significantly correlated with MS-related risk factors. The prevalence of MS and JMS was significantly higher in Q4 than in Q1 for both men and women and the prevalence of diabetes was significantly higher in Q4 than in Q1 in men.
