Abstract
Objective: With breast cancer screening being recommended more and more these days, an optimal screening procedure, through modality selection or combination of modalities, needs to be established to enhance the accuracy of screening. In this study, we examined the details of breast cancer identified in breast cancer screening in our hospital and conducted a clinical study of diagnostic accuracy for modality combination, which also considered screening interval.
Methods: The subjects of the study were 86 persons with a definite diagnosis of breast cancer in opportunistic and population-based breast cancer screening in our hospital between June 2009 and March 2013 and from whom informed consent was received. For combined mammography and ultrasonography screening, we compared cancer detection rates and clinical stages at diagnosis, conducted a current status survey on the subjects who received screening every year, and examined the usefulness of combined screening by the two methods.
Results: Of 86 subjects with breast cancer, 20 (23.3%) underwent combined mammography and ultrasonography screening in addition to clinical breast examination. By both methods, it was determined that detailed examination would be required for 65% (13/20). However, cancer was not detected in 20% (4/20) by ultrasonography and 15% (3/20) by mammography. Of the subjects who received screening every year, only 21.4% habitually received combined screening and regarding clinical stage, 63.6% (7/11) had ductal carcinoma in situ.
Conclusion: This study suggested that combined mammography and ultrasonography screening performed every year would reduce the non-detection rate of infiltration cancer.