Abstract
Objective: To examine differences in fundus photograph findings between metabolic syndrome (Mets) and non-Mets individuals.
Methods: Fundus photographs were examined for 2,189 men (average age: 48.3 ± 8.4yrs) and 728 women (47.4 ± 8.2yrs) who visited our health check-up division from May 6, 2011 to April 28, 2012.The images were diagnosed by ophthalmologists. We divided the examinees into two groups: Mets group and non-Mets group according to the Japanese diagnostic criteria of Mets, and examined the differences in fundus photograph findings between them. Statistical analysis was performed using the t test, the chi-square test, Fisher's exact test and the Cochran-Mantel-Haenszel test with p<0.05 regarded as significant.
Results: Among the total of 2,917 examinees, the number of Mets subjects was 408 and that of non-Mets subjects was 2,509. One hundred twenty eight (31.4%) of the 408 examinees in the Mets group and 489 (19.5%) of the 2,509 in the non-Mets group had abnormal findings in the fundus photographs. There was a significant relationship between Mets and abnormal findings, which included optic nerve cupping expansion, chorioretinal atrophy and diabetic retinopathy.
Conclusion: Mets examinees may have more ophthalmic disorders than non-Mets examinees.
