Abstract
The present study was conducted to examine the noninvasive Brachial-ankle pulse wave velocity (baPWV) /Ankle Brachial Index (ABI) measurements of the early stage of type II diabetes patients in our hospital. Compared with the normal control group, baPWV of the diabetic group was significantly increased (1594±31 vs1308±13 cm/sec, p<0.001). Although there were no diabetic factors which are significantly correlated with baPWV/ABI in a diabetic group, baPWV of the patients with microalbuminuria group was significantly increased (1758±55 vs1580±35 cm/sec, p<0.01). These data suggest that the arteriosclerosis of great vessels have already advanced also in the early stage of diabetes, and baPWV not only knows the grade of the arteriosclerosis of large vessels, but may be a useful predictor of development of diabetic nephropathy by arteriosclerosis of small vessels.
