Association Between Colorectal Adenoma and Lifestyle-related Diseases

Abstract

Objective: To elucidate the relationship between colorectal adenoma and lifestyle-related diseases.

Methods: We enrolled 227 individuals who underwent a complete medical checkup at Tokyo Women’s Medical University between June 2016 and December 2017. Risk factors related to the development of colorectal adenoma were analyzed by contingency tables using multivariate logistic regression. Statistical significance was set at p<0.05.

Results: Colorectal adenoma was significantly related to metabolic syndrome that comprises three components, namely central obesity with hypertension, dyslipidemia, and impaired fasting glucose.

Conclusions: The presence of the three components of metabolic syndrome, hypertension, dyslipidemia, and impaired fasting glucose, significantly increases the risk of colorectal adenoma. Therefore, in addition to medication and lifestyle improvements (e.g., diet, exercise therapy), participants with metabolic syndrome with these three components should undergo screening for colorectal adenoma.