The Nishinihon Journal of Dermatology
Online ISSN : 1880-4047
Print ISSN : 0386-9784
ISSN-L : 0386-9784
Laboratory Study
Evaluation of Treponema Pallidum Hemagglutination Test (TPHA Test), New Method Originated in Japan
Sachio TOTOKAWATakehide KIKUCHIKousaku MORITA
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1969 Volume 31 Issue 1 Pages 39-42

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Abstract
215 nonsyphilitic sera and 105 syphilitic sera were examined by TPHA test (to use as antigen formalin treated tanned sheep red blood cells sensitized by T. P. Nichols strain and testing sera absorbed with T. P. Reiter strain and etc.,).
Results:
1) On the nonsyphilitic sera 195 gave negative results to both of STS and TPHA, 6 gave positive results to TPHA and negative to STS, 14 gave negative results to TPHA and positive to STS. Then these were regarded as BFP, coinciding with results to FTA-200.
2) On the syphilitic sera
101 gave positive results to both of STS and TPHA. The reactivity to TPHA has been persistent after the antiluetic treatment. The sensitivity and spicificity of TPHA on syphilis might be satis-factory as that of FTA. Then the advantage of TPHA might be the stable graded agglutination figure on the hollow plastic plate for the test.
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© 1969 by Western Japan Division of JDA
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