Abstract
Two cases of so-called rhinitis gangrenosa progressiva are presented, which appeared in 30-year-old male and in 50-year-old female. Both cases had cutaneous lesions which were not clinically diagnostic. The biopsy specimens of these cutaneous lesions showed dense diffuse infiltrate in the middle and lower dermis and subcutaneous tissue. The infiltrate was composed of mainly lymphocytes and atypical reticulo-histiocytes. The appendages were surrounded by the abnormal cells without destruction of these architecture. The autopsy findings of these cases revealed malignant reticulosis. Malignant reticulosis should be included in the spectrum of so-called rhinitis gangrenosa progressiva.
