Abstract
Keratosis punctata palmaris et plantaris developed in a brother (72-year-old) and a sister (60-year-old). The lesions in both patients consisted of miliary to pin-head sized keratotic papules disseminated on their palms and soles. The papules showed a yellow-brownish colored surface with crateriform depression. Although a keratotic column penetrating to an eccrine sweat duct was seen on the biopsy specimens, particular pathological changes of the duct were nil. Heredodiathesis was apparent in these patients.