Abstract
A 39-year-old man had recurrent generalized skin rashes for about nine years. These rashes were accompanied by blood eosinophilia and cardiopulmonary abnormalities. The microscopic findings of the skin lesions were consistent with Wells’ original descriptions. The electron microscopic studies disclosed microtubular structures in the endothelial cells of the dermal vessels as well as dermal infiltration of lymphocytes and histiocytes. Nineteen cases reported to date were reviewed and the relationship to hypereosinophilic syndrome was discussed.