A Case of Polymorphous Light Eruption with Atypical Lymphocytic Infiltration in the Dermis

Abstract

A 66-year-old man had a two-year history of an eruption on exposed areas. A diagnosis of polymorphous light eruption was made six months before because of the induction of UVB abnormal reaction, with no other photosensitivity related disorders. Topical corticosteroid therapy was prescribed, but the eruption gradually worsened and he was re-admitted. MED was markedly decreased at this time, though the MED level during the previous hospitalization had been normal. Histopathlogical findings showed dense infiltration of lymphocytes with atypical lymphocytes in the dermis and ATL-antibody in the serum was positive. The correlation between ATL-antibody and atypical lymphocytes in this patient is controversial. As the atypical lymphocytes disappeared when the eruption was improved by photo-protection, we assumed that these cells may be induced by UVB.