The Nishinihon Journal of Dermatology
Online ISSN : 1880-4047
Print ISSN : 0386-9784
ISSN-L : 0386-9784
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Volume 48, Issue 4
Displaying 1-26 of 26 articles from this issue
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Color Atlas
Mini Review
Clinical Case Reports
  • Lichen Planus Associated with Ulcerative Lesions
    Yoshinori SUENAGA, Nobuaki TAKE, Kanichiro NAKAYAMA, Kiyoshi DOI
    1986 Volume 48 Issue 4 Pages 647-651
    Published: August 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.647
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    A 60-year-old woman with lichen planus on the extremities, in association with ulcerative lesions, was reported. Histopathological studies of the biopsy specimen showed typical findings of lichen planus and deposits of IgM, and IgG in the Civette body were revealed by direct immunofluorescence staining. Patch tests of dental metals were negative. Treatment with Dermovate cream and Drenison tape resulted in improvement of the lesions. This makes the fourth such case to be reported in Japan.
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  • Progressive Systemic Sclerosis Associated with Various Autoantibodies
    Kouzou OOKAWA, Jiro ARATA, Jingo SATO
    1986 Volume 48 Issue 4 Pages 652-655
    Published: August 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.652
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    A 20-year-old woman with progressive systemic sclerosis during 10 years was surgically treated for an acute abdomen, associated with high fever, in the summer of 1983. Since then, laboratory data revealed the presence of hypocomplimentemia, hyper-γ-globulinemia, anti-DNA-antibody, anti-nRNP-antibody, anti-Sm-antibody, LE cells, and a positive lupus band test. She was put on oral corticosteroids, and the scleroderma and pigmentation improved considerably. This case presents PSS overlapping with the immunological findings of SLE and it shares signs and symptoms of mesenchymal scleroderma (Winkelmann).
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  • A Case of Polymorphous Light Eruption with Atypical Lymphocytic Infiltration in the Dermis
    Hiroko IRIFUNE, Fumio MURAYAMA, Taro OHGAMI, Shigeo NONAKA, Hikotaro Y ...
    1986 Volume 48 Issue 4 Pages 656-659
    Published: August 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.656
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    A 66-year-old man had a two-year history of an eruption on exposed areas. A diagnosis of polymorphous light eruption was made six months before because of the induction of UVB abnormal reaction, with no other photosensitivity related disorders. Topical corticosteroid therapy was prescribed, but the eruption gradually worsened and he was re-admitted. MED was markedly decreased at this time, though the MED level during the previous hospitalization had been normal. Histopathlogical findings showed dense infiltration of lymphocytes with atypical lymphocytes in the dermis and ATL-antibody in the serum was positive. The correlation between ATL-antibody and atypical lymphocytes in this patient is controversial. As the atypical lymphocytes disappeared when the eruption was improved by photo-protection, we assumed that these cells may be induced by UVB.
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  • A Case of Fournier’s Gangrene (Fulminating Gangrene of the Male Genitalia) Associated with Eruptions Appearing as Pyoderma Gangrenosum
    Nobuyuki SHIRAISHI, Satoshi ITAMI, Shunichiro SEGUCHI, Susumu TAKAYASU
    1986 Volume 48 Issue 4 Pages 660-664
    Published: August 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.660
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    We treated a man with Fournier’s gangrene (fulminating gangrene of the male genitalia) associated with eruptions appearing as pyoderma gangrenosum. This 64-year-old man was admitted to the hospital with painful penile gangrene. He had no apparent history of previous infection. Significant in the history was therapy with diaminodiphenyl sulphone (DDS) for eruptions appearing as pyoderma gangrenosum on the extremities and buttock of 8 months duration. Cultures yielded Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus faecalis. Despite serial débridement of all necrotic tissue of the penis, combined with systemic administration of broadspectrum antibiotics his condition continued to deteriorate. His body temperature was high and gangrene progressively developed in the penis and scrotum, necessitating bilateral orchiectomy and amputation of the penis. The clinical course and pathological feature were compatible with those reported as Fournier’s gangrene. Preexisting eruptions and DDS administration seemed to be the predisposing conditions, but the source of infection may be difficult to identify in this case.
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  • A Case of Cronkhite-Canada Syndrome
    Taketsugu HATANO, Shingo TSUDA, Yoichiro SASAI, Tadashi IWAO, Kazuaki ...
    1986 Volume 48 Issue 4 Pages 665-670
    Published: August 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.665
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    A 50-year-old woman with Cronkhite-Canada syndrome had gastrointestinal polyposis associated with alopecia, onychotrophia and skin pigmentation. A skin specimen from a pigmented area on the palm showed a marked accumulation of melanin in the basal layer. Clinical symptoms, including skin manifestations, improved after treatment with intravenous hyperalimentation and oral administration of corticosteroid.
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  • A Case of Peculiar Hair Cysts Arising in the Skin of Both Postauricular Areas
    Masao SUWAKI
    1986 Volume 48 Issue 4 Pages 671-674
    Published: August 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.671
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    A 55-year-old woman noted progressive development of randomly scattered miliary papules involving both postauricular areas, symmetrically, over a decade. Histologically, the cysts were located in the mid-dermis and contained laminated keratinous material as well as vellus hairs. Though hair cysts do resemble primary milium, they differ from milium which usually occurs on the face and may be more superficially located in the dermis, histologically. This case was practically the same as eruptive vellus hair cysts (E. V. H. C.) located in the mid-dermis. However, precluding the diagnosis of E. V. H. C., two aspects were noted. First, the hair cysts arose in a peculiar region, not heretofore reported. Secondly, the hair cysts in this case clinically resembled milium rather than E. V. H. C.. Milia en plaque may also be considered, however, such has a predilection for the face and a tendency to aggregate to form a plaque unilaterally. This case is unique and does not fit the diagnosis as any of the above mentioned epidermal cysts.
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  • A Case of Chromosome Eighteen Trisomy Syndrome with Hypertrichosis
    Shigeo NONAKA, Taro OHGAMI, Fumio MURAYAMA, Tadashi MASUMOTO
    1986 Volume 48 Issue 4 Pages 675-677
    Published: August 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.675
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    Chromosome eighteen trisomy syndrome is a multiple malformation syndrome with chromosomal abnormalities. There are very few related reports in the field of dermatology. A 4-day-old female child was seen in our clinic because of hypertrichosis. She was born on Mar. 26, 1983. Pregnancy and delivery were apparently normal. At the time of birth, the mother was 27 and the father 28. There was no consanguinity. The patient weighted 1,920 gm and was sent to our center for premature babies because of cyanosis, low weight, heart murmur and ectodermal malformation. The ears were low set with slight malformation of the auricles. The nose seemed normal except for a slight obstruction of the post pharyngeal region. Overlapping fingers and a short sternum were present. Systolic murmur was heard in the III and IV intercostal space. Findings of overriding aorta, and high VSD and ASD were observed on the heart echogram. There appeared to be hypertonia in the extremities. The number of chromosomes was 47 in the peripheral blood culture and eighteen trisomy was confirmed. Dermatologically, there was redness of the skin, and punctate purpura or the abdominal region. Short, hard, black hair was present over the back, buttocks and extremities. Histopathologically, the number of follicles was increased. There were no changes in the morphology of the hair follicles. The infant died of respiratory insufficiency on the 23rd postnatal day.
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  • A Case of Bourneville-Pringle Phakomatosis with the Chief Complaint of Bleeding from a Verrucous Facial Lesion
    Yumiko SAKURAI, Emiko OKABE, Taro KAWAMURA, Kimiko TAJIMA, Shigeo IKED ...
    1986 Volume 48 Issue 4 Pages 678-682
    Published: August 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.678
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    Manifestations of Bourneville-Pringle phakomatosis (B.-P. Ph.) are determined by dissemination of mesenchymal phakomatoblasts in the early embryonic stage and differ extremely among individual cases. The chief complaint of a 61-year-old man was bleeding from a verrucous lesion on his cheek. The epidermal area of the lesion was seborrheic keratosis-like, the superfical half of the dermis was composed of “angiofibromatous” tissue lacking elastic fiber. In another facial lesion, “solar degeneration” was evident in the dermal tissue, without elastic fiber. These observations may support an explanation of the cause of the solar elastosis, i. e. not degeneration of pre-existing elastic fibers but rather altered function of fibroblasts (Lever & Schaumberg-Lever, 6th. Ed., 1983). The patient was diagnosed as a case of B.-P. Ph. by clinical and microscopic findings of the lesions. The diagnosis was supported by calcified sub-ependymal nodules seen on the brain CT and positive fluorescence funduscopy. No abnormality was found in pyelograms and chest X-ray. On consideration of the present case and ones hitherto reported, attention should be drawn to the following items:
    (1) Five (including the present) cases living over 60 years have been reported in Japan. Their mental deficiency was slight, occurred in the latest stage of their life or was lacking. All but one were males.
    (2) Cases of B.-P. Ph. without mental retardation are common.
    (3) Efficacious means for diagnosing B.-P. Ph are clinical and histological examination of skin lesions, along with funduscopy, brain CT, pyelography and chest X-ray.
    (4) Lesions may bleed, and serious sequelae may follow this bleeding.
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  • Three Cases of Secondary Syphilis
    Emiko NOZAKI, Masanori TSUCHIYA, Toshiko CHIBA, Nagayoshi SHIMODA, Ken ...
    1986 Volume 48 Issue 4 Pages 683-689
    Published: August 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.683
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    We treated 3 patients with secondary syphilis, originally contacted from each other during their high school days. One was a 19-year-old girl with condyloma latum, a 19-year-old boy with syphilis papulosa and an 18-year-old girl with roseola syphilitica and condyloma latum. Statistical data on the frequency of cases of early syphilis seen by our department from 1978 to 1984 are also presented.
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  • A Case of Eccrine Spiradenoma
    Yuji INOUE, Kimiko TAKAISHI, Keiichi UEDA, Michio BANBA
    1986 Volume 48 Issue 4 Pages 690-692
    Published: August 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.690
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    We report a case of eccrine spiradenoma in a 58-year-old man who noticed a nodule associated with tenderness and radiating pain on the right side of the abdomen. Typical features were detected histologically. Further, in 45 cases of this disease reported in Japan including the present case, statistical evaluations on clinical findings were made, and discussion is made on the malignant cases of this tumor outlined in the literature.
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Clinical and Investigative Report
  • Radiodermatitis—An Analysis of 43 Occurrences at Miyazaki Medical College
    Michiharu OKAZAKI, Hiromi NARITA, Katsumi OGATA, Shouhei INOUE
    1986 Volume 48 Issue 4 Pages 693-699
    Published: August 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.693
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    Forty-three cases of acute and chronic radiodermatitis, which occurred in the Department of Dermatology, Miyazaki Medical College between November 1977 and April 1985 were studied. Fifteen were acute and 28 were chronic. All of the original conditions treated presenting acute radiodermatitis were malignancies. Among 28 with chronic radiodermatitis, 17 had been given radiotherapy for benign conditions and 7 cases for malignant lesions. The remaining 4 were of occupational origin. Of the 28 cases with chronic radiodermatitis, histological examination was performed on 23 cases. Chronic radiodermatitis showed the following histological findings; mild atypia in 9 (all poikilodermatous lesions showed at least mild atypia), intra-epidermal carcinoma in 6, squamous cell carcinoma in 7 and sarcoma (malignant fibrous histiocytoma) in 1. The keratotic lesions of radiodermatitis of the hands and feet tended to malignant, as compared to lesions in other areas.
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  • Port Wine Stain and Response to Argon Laser Therapy:
    Prediction of Color Differences Between Lesional and Normal Skin
    Tomomitsu NAKANO, Tadashi TEZUKA
    1986 Volume 48 Issue 4 Pages 700-702
    Published: August 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.700
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    Argon laser therapy is effective for some, but not all, cases of port wine stain (PWS). To determine the predictive role of PWS color, color differences between lesional and normal skin were measured, using a color and color difference meter. The response to the argon laser treatment was determined in 170 patients with PWS. Good to excellent results occurred in case of a skin eruption which was sharply bordered and intensively red, with remarkable telangiectasia. The mean value of the color difference was 3.95±1.24 NBS in 57 patients. Poor results occurred in a less red exanthema with lack of telangiectasia. The mean value of the color difference was 1.73±0.88 NBS in 46 patients. Fair results occurred in case of a skin lesion between the two, as described above. The mean value of the color difference was 3.18±1.13 NBS in 67 patients. There were statistically significant differences at the 0.05 level among the three groups. In conclusion, using a color and color difference meter, the therapeutic response of PWS to argon laser treatment can be predicted prior to the treatment.
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  • Spontaneous Healing of Hand Eczema in Children
    Kuninobu SONODA, Katsuro OHYAMA, Yoshihiro MAEKAWA
    1986 Volume 48 Issue 4 Pages 703-706
    Published: August 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.703
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    It is sometimes difficult for a clinician to differentiate eczema-dermatitis group of the hands. We report herein cases of hand eczema in children, with characteristic clinical features. These eruptions were similar to the pompholyx which is seen mostly in the spring and fall. We found no related allergens. Topical corticosteroid was without effect and spontaneous healing occurred within 2∼3 weeks. The pathogenesis of this type of hand eczema may relate to both internal and enviromental factors, as well as to a virus.
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  • Alterations in Various Serological Tests’ Titers for Syphilis, in Primary and Secondary Cases
    Mariko SEISHIMA, Yasushi MORI, Takashi OHTA, Michihiro OHTANI, Yasuko ...
    1986 Volume 48 Issue 4 Pages 707-714
    Published: August 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.707
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    Statistical observations were made on 27 patients with syphilis (primary syphilis: 19 cases, secondary syphilis: 8 cases) in the Dermatological Clinic of Gifu Prefectural Gifu Hospital from January 1983 to April 1985. BAPC (1,500 mg/day) was administered for 2 weeks to the patients with primary syphilis and for 4 weeks to those with secondary syphilis. We examined various serological tests for syphilis (TPHA, TPHA-IgM, FTA-ABS, IgM-FTA-ABS, compliment fixation test for syphilis and VDRL) before the treatment, and 1 week, 2 weeks, 3 weeks, 4 weeks, 6 weeks, 2 months, 3 months, 4 months and 6 months later. The IgM class antitreponemal antibody became negative after 8.1 weeks, on the average from the beginning of the treatment in the cases of primary syphilis. And it became negative after 11.1 weeks, on the average in the cases of secondary syphilis.
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  • Open Treatment for Skin Defects Following Resection of a Tumor on the Lower Eyelid
    Takashi HASEGAWA, Masako KOBAYASHI, Kazuhiko YORIFUJI, Tatsuya ITOH, H ...
    1986 Volume 48 Issue 4 Pages 715-719
    Published: August 01, 1986
    Released on J-STAGE: March 15, 2012
    DOIhttps://doi.org/10.2336/nishinihonhifu.48.715
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    Open treatment for a skin defect following resection of a tumor is given to aid spontaneous wound healing, without primary closure or reconstructive repair. Eleven patients with a tumor on the lower eyelid were treated by this method, 3 of the lateral, 5 of the medial, 3 of the mid-portion. All wounds healed within 2 weeks and good results were obtained. Since this method is simple and less affected by the operation, it is recommended for treating geriatric patients or those with serious complications.
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