A Case of Cronkhite-Canada Syndrome

Abstract

A 50-year-old woman with Cronkhite-Canada syndrome had gastrointestinal polyposis associated with alopecia, onychotrophia and skin pigmentation. A skin specimen from a pigmented area on the palm showed a marked accumulation of melanin in the basal layer. Clinical symptoms, including skin manifestations, improved after treatment with intravenous hyperalimentation and oral administration of corticosteroid.