Alterations in Various Serological Tests’ Titers for Syphilis, in Primary and Secondary Cases

Abstract

Statistical observations were made on 27 patients with syphilis (primary syphilis: 19 cases, secondary syphilis: 8 cases) in the Dermatological Clinic of Gifu Prefectural Gifu Hospital from January 1983 to April 1985. BAPC (1,500 mg/day) was administered for 2 weeks to the patients with primary syphilis and for 4 weeks to those with secondary syphilis. We examined various serological tests for syphilis (TPHA, TPHA-IgM, FTA-ABS, IgM-FTA-ABS, compliment fixation test for syphilis and VDRL) before the treatment, and 1 week, 2 weeks, 3 weeks, 4 weeks, 6 weeks, 2 months, 3 months, 4 months and 6 months later. The IgM class antitreponemal antibody became negative after 8.1 weeks, on the average from the beginning of the treatment in the cases of primary syphilis. And it became negative after 11.1 weeks, on the average in the cases of secondary syphilis.